Dirk, a Pokémon Hunter tried to capture Mewtwo in the mountainous region of Unova and return it to his clients. He explained that Mewtwo was created by humans by using Mew's genes as base. It was created to be the strongest Pokémon but Mewtwo was abused for experiments. However, having grown distrustful of humans, Mewtwo destroyed the research facility and fled.
Dirk lied and said he was searching for Mewtwo to offer it protection.
One day when
Oscar was hiking in the mountains with
Anna, the cliff gave way and she began to slide down. Mooland came to her rescue but just as she was about to be rescued by
Oscar, the cliff also gave way on him and they all fell off the cliff. They ended up being saved by Mewtwo who quickly disappeared.
Oscar's Stoutland brought Mewtwo a Revival Herb after searching the forest for it.
Anna didn't know that
Dirk lied to them and was a bad person but Mewtwo seemed to trust her and understand the situation despite its distrust of humans.